OPA1-anchored PKA phosphorylates perilipin 1 on S522 and S497 in adipocytes differentiated from human adipose stem cells

Optic atrophy 1 (OPA1) is the A-kinase anchoring protein targeting the pool of protein kinase A (PKA) responsible for perilipin 1 phosphorylation, a gatekeeper for lipolysis. However, the involvement of OPA1-bound PKA in the downstream regulation of lipolysis is unknown. Here we show up-regulation a...

Descripción completa

Detalles Bibliográficos
Autores principales: Rogne, Marie, Chu, Dinh-Toi, Küntziger, Thomas M., Mylonakou, Maria-Niki, Collas, Philippe, Tasken, Kjetil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014102/
https://www.ncbi.nlm.nih.gov/pubmed/29688805
http://dx.doi.org/10.1091/mbc.E17-09-0538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014102/
https://www.ncbi.nlm.nih.gov/pubmed/29688805
http://dx.doi.org/10.1091/mbc.E17-09-0538

Ejemplares similares