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OPA1-anchored PKA phosphorylates perilipin 1 on S522 and S497 in adipocytes differentiated from human adipose stem cells

Optic atrophy 1 (OPA1) is the A-kinase anchoring protein targeting the pool of protein kinase A (PKA) responsible for perilipin 1 phosphorylation, a gatekeeper for lipolysis. However, the involvement of OPA1-bound PKA in the downstream regulation of lipolysis is unknown. Here we show up-regulation a...

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Detalles Bibliográficos
Autores principales:	Rogne, Marie, Chu, Dinh-Toi, Küntziger, Thomas M., Mylonakou, Maria-Niki, Collas, Philippe, Tasken, Kjetil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014102/ https://www.ncbi.nlm.nih.gov/pubmed/29688805 http://dx.doi.org/10.1091/mbc.E17-09-0538

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