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Low-Dose 4-Hydroxy-2-Nonenal (HNE) Reperfusion Therapy Displays Cardioprotective Effects in Mice After Myocardial Infarction That Are Abrogated by Genipin

BACKGROUND: Revascularization is a successful therapeutic strategy for myocardial infarction. However, restoring coronary blood flow can lead to ischemia-reperfusion (I/R) injury. Low-dose 4-hydroxy-2-nonenal (HNE) therapy appears to play a key role in myocardial tolerance to I/R injury. We hypothes...

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Detalles Bibliográficos
Autores principales: Wang, Ying-nan, Gao, Lei, Wu, Shi-Yong, Qin, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014150/
https://www.ncbi.nlm.nih.gov/pubmed/29858912
http://dx.doi.org/10.12659/MSM.910494