Highly efficient synthesis and stereoselective migration reactions of chiral five-membered aza-spiroindolenines: scope and mechanistic understanding

An Ir-catalyzed asymmetric synthesis of five-membered aza-spiroindolenines is achieved. Based on the detailed investigation of the reaction patterns of the aryl iminium migration, a one-pot asymmetric allylic dearomatization/migration sequence from racemic indole derivatives is realized, affording e...

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Detalles Bibliográficos
Autores principales: Wu, Qing-Feng, Zheng, Chao, Zhuo, Chun-Xiang, You, Shu-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014299/
https://www.ncbi.nlm.nih.gov/pubmed/30155093
http://dx.doi.org/10.1039/c6sc00176a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014299/
https://www.ncbi.nlm.nih.gov/pubmed/30155093
http://dx.doi.org/10.1039/c6sc00176a

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