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Calcium oxalate crystals induces tight junction disruption in distal renal tubular epithelial cells by activating ROS/Akt/p38 MAPK signaling pathway

Tight junction plays important roles in regulating paracellular transports and maintaining cell polarity. Calcium oxalate monohydrate (COM) crystals, the major crystalline composition of kidney stones, have been demonstrated to be able to cause tight junction disruption to accelerate renal cell inju...

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Detalles Bibliográficos
Autores principales: Yu, Lei, Gan, Xiuguo, Liu, Xukun, An, Ruihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014313/
https://www.ncbi.nlm.nih.gov/pubmed/28335665
http://dx.doi.org/10.1080/0886022X.2017.1305968