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The impact of PI3K inhibitors on breast cancer cell and its tumor microenvironment

The phosphoinositide 3-kinase (PI3K) pathway shows frequent aberrant alterations and pathological activation in breast cancer cells. While PI3K inhibitors have not achieved expectant therapeutic efficacy in clinical trials, and several studies provide promising combination strategies to substantiall...

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Detalles Bibliográficos
Autores principales: Qin, Hanjiao, Liu, Linlin, Sun, Shu, Zhang, Dan, Sheng, Jiyao, Li, Bingjin, Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014315/
https://www.ncbi.nlm.nih.gov/pubmed/29942710
http://dx.doi.org/10.7717/peerj.5092