CYP3A and CYP2C19 activity in urine in relation to CYP3A4, CYP3A5, and CYP2C19 polymorphisms in Russian peptic ulcer patients taking omeprazole

BACKGROUND: Proton pump inhibitors (PPIs) are metabolized by cytochrome P450. CYP2C19 is the main isoenzyme for the majority of PPI, whereas CYP3A family is a secondary enzyme for PPI biotransformation. PURPOSE: The aim of the study was to find if CYP3A4*22, CYP3A5*3, CYP2C19*2, CYP2C19*3, and CYP2C...

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Detalles Bibliográficos
Autores principales: Denisenko, Natalia P, Sychev, Dmitriy A, Sizova, Zhanna M, Smirnov, Valeriy V, Ryzhikova, Kristina A, Sozaeva, Zhannet A, Grishina, Elena A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014385/
https://www.ncbi.nlm.nih.gov/pubmed/29950882
http://dx.doi.org/10.2147/PGPM.S159708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014385/
https://www.ncbi.nlm.nih.gov/pubmed/29950882
http://dx.doi.org/10.2147/PGPM.S159708

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