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A rapid and reliable chromosome analysis method for products of conception using interphase nuclei

BACKGROUND: Karyotype determination has a central role in the genetic workup of pregnancy loss, as aneuploidy (trisomy and monosomy) and polyploidy (triploidy and tetraploidy) are the cause in at least 50% of first trimester, 25% of second trimester, and 11% of third trimester miscarriages. There ar...

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Detalles Bibliográficos
Autores principales: Babu, Ramesh, Van Dyke, Daniel L., Bhattacharya, Saurabh, Dev, Vaithilingam G., Liu, Mingya, Kwon, Minjae, Gu, Guangyu, Koduru, Prasad, Rao, Nagesh, Williamson, Cynthia, Fuentes, Ernesto, Fuentes, Sarah, Papa, Stephen, Kopuri, Srikanthi, Lal, Vandana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014463/
https://www.ncbi.nlm.nih.gov/pubmed/29573570
http://dx.doi.org/10.1002/mgg3.381