Low-dose IL-2 expands CD4(+) regulatory T cells with a suppressive function in vitro via the STAT5-dependent pathway in patients with chronic kidney diseases

Background: Patients with chronic kidney disease (CKD) often have CD4+ regulatory T cells (Tregs) dysfunction and chronic inflammation. We aim to investigate the effect, function, and related mechanism of low-dose IL-2 on CD4(+) regulatory T cells expansion in vitro from patients with CKD. Methods:...

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Detalles Bibliográficos
Autores principales: Li, Yuanyuan, Liu, Xueyong, Wang, Wei, Wang, Shaohua, Zhang, Jianchun, Jiang, Song, Wang, Yang, Li, Liping, Li, Jinghua, Zhang, Youkang, Huang, Haichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Laboratory Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014482/
https://www.ncbi.nlm.nih.gov/pubmed/29619880
http://dx.doi.org/10.1080/0886022X.2018.1456462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014482/
https://www.ncbi.nlm.nih.gov/pubmed/29619880
http://dx.doi.org/10.1080/0886022X.2018.1456462

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