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SOX30 Inhibits Tumor Metastasis through Attenuating Wnt-Signaling via Transcriptional and Posttranslational Regulation of β-Catenin in Lung Cancer

Although high mortality of lung cancer is greatly due to distant metastasis, the mechanism of this metastasis remains unclear. Here, we investigate in lung cancer that SOX30 is sharply under-expressed in metastatic tumors compared with non-metastatic tumors, and suppresses plenty of metastasis relat...

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Detalles Bibliográficos
Autores principales: Han, Fei, Liu, Wen-bin, Shi, Xiao-yan, Yang, Jun-tang, Zhang, Xi, Li, Zhi-ming, Jiang, Xiao, Yin, Li, Li, Jian-jun, Huang, Chuan-shu, Cao, Jia, Liu, Jin-yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014586/
https://www.ncbi.nlm.nih.gov/pubmed/29739711
http://dx.doi.org/10.1016/j.ebiom.2018.04.026