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Deep sequencing of HIV-1 reverse transcripts reveals the multifaceted anti-viral functions of APOBEC3G

Following cell entry, the RNA genome of HIV-1 is reverse transcribed into double-stranded DNA that ultimately integrates into the host cell genome to establish the provirus. These early phases of infection are notably vulnerable to suppression by a collection of cellular anti-viral effectors, called...

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Detalles Bibliográficos
Autores principales: Pollpeter, Darja, Parsons, Maddy, Sobala, Andrew E., Coxhead, Sashika, Lang, Rupert D., Bruns, Annie M., Papaioannou, Stelios, McDonnell, James M., Apolonia, Luis, Chowdhury, Jamil A., Horvath, Curt M., Malim, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014619/
https://www.ncbi.nlm.nih.gov/pubmed/29158605
http://dx.doi.org/10.1038/s41564-017-0063-9