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Deep sequencing of HIV-1 reverse transcripts reveals the multifaceted anti-viral functions of APOBEC3G
Following cell entry, the RNA genome of HIV-1 is reverse transcribed into double-stranded DNA that ultimately integrates into the host cell genome to establish the provirus. These early phases of infection are notably vulnerable to suppression by a collection of cellular anti-viral effectors, called...
Autores principales: | Pollpeter, Darja, Parsons, Maddy, Sobala, Andrew E., Coxhead, Sashika, Lang, Rupert D., Bruns, Annie M., Papaioannou, Stelios, McDonnell, James M., Apolonia, Luis, Chowdhury, Jamil A., Horvath, Curt M., Malim, Michael H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014619/ https://www.ncbi.nlm.nih.gov/pubmed/29158605 http://dx.doi.org/10.1038/s41564-017-0063-9 |
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