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Cadmium-Associated Differential Methylation throughout the Placental Genome: Epigenome-Wide Association Study of Two U.S. Birth Cohorts

BACKGROUND: Cadmium (Cd) is a ubiquitous environmental toxicant that can accumulate in the placenta during pregnancy, where it may impair placental function and affect fetal development. OBJECTIVES: We aimed to investigate Cd-associated variations in placental DNA methylation (DNAM) and associations...

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Detalles Bibliográficos
Autores principales: Everson, Todd M., Punshon, Tracy, Jackson, Brian P., Hao, Ke, Lambertini, Luca, Chen, Jia, Karagas, Margaret R., Marsit, Carmen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014712/
https://www.ncbi.nlm.nih.gov/pubmed/29373860
http://dx.doi.org/10.1289/EHP2192