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The Relationship between insulin variable number of tandem repeats (INS-VNTR) -23 A/T and cytotoxic Tlymphocyte associated protein-4 (CTLA-4) +49 A/G polymorphisms with islet autoantibodies in persons with diabetes

Background: Both genetic and environmental factors are important in pathogenesis of diabetes. Non HLA (Human Leukocyte Antigen) genes such as INS-VNTR and CTLA-4 in addition of HLA genes have influence on genetic susceptibility for diabetes mellitus. In this study the association of +49 A/G CTLA-4 a...

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Detalles Bibliográficos
Autores principales: Khoshroo, Mohammad, Khamseh, Mohammad Ebrahim, Amir Zargar, Ali Akbar, Malek, Mojtaba, Falak, Reza, Shekarabi, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iran University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014810/
https://www.ncbi.nlm.nih.gov/pubmed/29951384
http://dx.doi.org/10.18869/mjiri.31.83