Piperlongumine and p53-Reactivator APR-246 Selectively Induce Cell Death in HNSCC by Targeting GSTP1

TP53 mutations frequently occur in head and neck squamous cell carcinoma (HNSCC) patients without human papillomavirus infection. The recurrence rate for these patients is distinctly high. It has been actively explored to identify agents that target TP53 mutations and restore wild-type (WT) TP53 act...

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Detalles Bibliográficos
Autores principales: Hang, Wei, Yin, Zhi-Xian, Liu, Gang, Zeng, Qinghua, Shen, Xiang-Feng, Sun, Qian-Hui, Li, Dong-Dong, Jian, Yong-Ping, Zhang, Yang-He, Wang, Yi-Shu, Quan, Cheng-Shi, Zhao, Rui-Xun, Li, Yu-Lin, Xu, Zhi-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014869/
https://www.ncbi.nlm.nih.gov/pubmed/29348462
http://dx.doi.org/10.1038/s41388-017-0110-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014869/
https://www.ncbi.nlm.nih.gov/pubmed/29348462
http://dx.doi.org/10.1038/s41388-017-0110-2

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