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Development of a dietary formulation of the SHetA2 chemoprevention drug for mice

Development of cancer chemoprevention compounds requires enhanced consideration for toxicity and route of administration because the target population is healthy. The small molecule drug, SHetA2 (NSC 726189), exhibited in vivo chemoprevention activity and lack of toxicity when administered by oral g...

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Detalles Bibliográficos
Autores principales: Benbrook, Doris M., Janakiram, Naveena B., Chandra, Vishal, Pathuri, Gopal, Madka, Venkateshwar, Stratton, Nicole C., Masamha, Chioniso P., Farnsworth, Cassadie N., Garcia-Contreras, Lucila, Hatipoglu, Manolya Kukut, Lighfoot, Stan, Rao, Chinthalapally V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014882/
https://www.ncbi.nlm.nih.gov/pubmed/29273857
http://dx.doi.org/10.1007/s10637-017-0550-0