Second-Generation DNA-Templated Macrocycle Libraries for the Discovery of Bioactive Small Molecules

DNA-encoded libraries have emerged as a widely used resource for discovery of bioactive small molecules and offer substantial advantages compared to conventional small-molecule libraries. Here we developed and streamlined multiple fundamental aspects of DNA-encoded and DNA-templated library synthesi...

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Detalles Bibliográficos
Autores principales: Usanov, Dmitry L., Chan, Alix I., Maianti, Juan Pablo, Liu, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014893/
https://www.ncbi.nlm.nih.gov/pubmed/29610462
http://dx.doi.org/10.1038/s41557-018-0033-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014893/
https://www.ncbi.nlm.nih.gov/pubmed/29610462
http://dx.doi.org/10.1038/s41557-018-0033-8

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