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Second-Generation DNA-Templated Macrocycle Libraries for the Discovery of Bioactive Small Molecules

DNA-encoded libraries have emerged as a widely used resource for discovery of bioactive small molecules and offer substantial advantages compared to conventional small-molecule libraries. Here we developed and streamlined multiple fundamental aspects of DNA-encoded and DNA-templated library synthesi...

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Detalles Bibliográficos
Autores principales:	Usanov, Dmitry L., Chan, Alix I., Maianti, Juan Pablo, Liu, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014893/ https://www.ncbi.nlm.nih.gov/pubmed/29610462 http://dx.doi.org/10.1038/s41557-018-0033-8

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