Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP

Natriuretic peptides (NPs) are important hormones that regulate multiple cellular functions including cardiovascular physiology. In the heart, two natriuretic peptide receptors NPR1 and NPR2 act as membrane guanylyl cyclases to produce 3′,5′-cyclic guanosine monophosphate (cGMP). Although both recep...

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Detalles Bibliográficos
Autores principales: Subramanian, Hariharan, Froese, Alexander, Jönsson, Peter, Schmidt, Hannes, Gorelik, Julia, Nikolaev, Viacheslav O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014982/
https://www.ncbi.nlm.nih.gov/pubmed/29934640
http://dx.doi.org/10.1038/s41467-018-04891-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014982/
https://www.ncbi.nlm.nih.gov/pubmed/29934640
http://dx.doi.org/10.1038/s41467-018-04891-5

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