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Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP
Natriuretic peptides (NPs) are important hormones that regulate multiple cellular functions including cardiovascular physiology. In the heart, two natriuretic peptide receptors NPR1 and NPR2 act as membrane guanylyl cyclases to produce 3′,5′-cyclic guanosine monophosphate (cGMP). Although both recep...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014982/ https://www.ncbi.nlm.nih.gov/pubmed/29934640 http://dx.doi.org/10.1038/s41467-018-04891-5 |