Cargando…

Sequential Application of Discrete Topographical Patterns Enhances Derivation of Functional Mesencephalic Dopaminergic Neurons from Human Induced Pluripotent Stem Cells

Parkinson’s Disease is a progressive neurodegenerative disorder attributed to death of mesencephalic dopaminergic (DA) neurons. Pluripotent stem cells have great potential in the study for this late-onset disease, but acquirement of cells that are robust in quantity and quality is still technically...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Kenneth K. B., Lim, Wallie Wee Meng, Chai, Chou, Kukumberg, Marek, Lim, Kah Leong, Goh, Eyleen L. K., Yim, Evelyn K. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014983/
https://www.ncbi.nlm.nih.gov/pubmed/29934644
http://dx.doi.org/10.1038/s41598-018-27653-1