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Sequential Application of Discrete Topographical Patterns Enhances Derivation of Functional Mesencephalic Dopaminergic Neurons from Human Induced Pluripotent Stem Cells
Parkinson’s Disease is a progressive neurodegenerative disorder attributed to death of mesencephalic dopaminergic (DA) neurons. Pluripotent stem cells have great potential in the study for this late-onset disease, but acquirement of cells that are robust in quantity and quality is still technically...
Autores principales: | Tan, Kenneth K. B., Lim, Wallie Wee Meng, Chai, Chou, Kukumberg, Marek, Lim, Kah Leong, Goh, Eyleen L. K., Yim, Evelyn K. F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014983/ https://www.ncbi.nlm.nih.gov/pubmed/29934644 http://dx.doi.org/10.1038/s41598-018-27653-1 |
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