A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity

MicroRNAs (miRNAs) regulate a majority of protein-coding genes, affecting nearly all biological pathways. However, the quantitative dimensions of miRNA-based regulation are not fully understood. In particular, the implications of miRNA target site location, composition rules for multiple target site...

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Detalles Bibliográficos
Autores principales: Gam, Jeremy J., Babb, Jonathan, Weiss, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014984/
https://www.ncbi.nlm.nih.gov/pubmed/29934631
http://dx.doi.org/10.1038/s41467-018-04575-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014984/
https://www.ncbi.nlm.nih.gov/pubmed/29934631
http://dx.doi.org/10.1038/s41467-018-04575-0

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