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A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity
MicroRNAs (miRNAs) regulate a majority of protein-coding genes, affecting nearly all biological pathways. However, the quantitative dimensions of miRNA-based regulation are not fully understood. In particular, the implications of miRNA target site location, composition rules for multiple target site...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014984/ https://www.ncbi.nlm.nih.gov/pubmed/29934631 http://dx.doi.org/10.1038/s41467-018-04575-0 |