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NMDA-receptor inhibition and oxidative stress during hippocampal maturation differentially alter parvalbumin expression and gamma-band activity

Dysfunction of parvalbumin (PV)-expressing interneurons is thought to underlie the alterations of gamma-band oscillations observed in schizophrenia. Although the pathomechanisms of this disease remain unclear, oxidative stress induced by NMDA receptor (NMDAR) hypofunction and decreased glutathione (...

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Detalles Bibliográficos
Autores principales: Hasam-Henderson, Luisa A., Gotti, Grace C., Mishto, Michele, Klisch, Constantin, Gerevich, Zoltan, Geiger, Jörg R. P., Kovács, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015018/
https://www.ncbi.nlm.nih.gov/pubmed/29934499
http://dx.doi.org/10.1038/s41598-018-27830-2