Estrogen promotes progression of hormone-dependent breast cancer through CCL2-CCR2 axis by upregulation of Twist via PI3K/AKT/NF-κB signaling

The chemokine (C-C motif) ligand 2 (CCL2) with its cognate receptor chemokine (C-C motif) receptor 2 (CCR2) plays important roles in tumor invasion and metastasis. However, the mechanisms and mediators for autocrine CCL2 and CCL2-CCR2 axis remain elusive in breast cancer. Here we examined the levels...

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Detalles Bibliográficos
Autores principales: Han, Rui, Gu, Shanzhi, Zhang, Yujiao, Luo, Anqi, Jing, Xin, Zhao, Lin, Zhao, Xinhan, Zhang, Lingxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015029/
https://www.ncbi.nlm.nih.gov/pubmed/29934505
http://dx.doi.org/10.1038/s41598-018-27810-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015029/
https://www.ncbi.nlm.nih.gov/pubmed/29934505
http://dx.doi.org/10.1038/s41598-018-27810-6

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