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Cysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity
Ovarian cancer is the second most common gynaecologic malignancy and the main cause of death from gynaecologic cancer, due to late diagnosis and chemoresistance. Studies have reported the role of cysteine in cancer, by contributing for hydrogen sulphide (H(2)S) generation and as a precursor of gluta...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015047/ https://www.ncbi.nlm.nih.gov/pubmed/29934500 http://dx.doi.org/10.1038/s41598-018-27753-y |