Bayesian Multi-Plate High-Throughput Screening of Compounds

High-throughput screening of compounds (chemicals) is an essential part of drug discovery, involving thousands to millions of compounds, with the purpose of identifying candidate hits. Most statistical tools, including the industry standard B-score method, work on individual compound plates and do n...

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Detalles Bibliográficos
Autores principales: Shterev, Ivo D., Dunson, David B., Chan, Cliburn, Sempowski, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015058/
https://www.ncbi.nlm.nih.gov/pubmed/29934615
http://dx.doi.org/10.1038/s41598-018-27531-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015058/
https://www.ncbi.nlm.nih.gov/pubmed/29934615
http://dx.doi.org/10.1038/s41598-018-27531-w

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