LIM Protein Ajuba associates with the RPA complex through direct cell cycle-dependent interaction with the RPA70 subunit

DNA damage response pathways are essential for genome stability and cell survival. Specifically, the ATR kinase is activated by DNA replication stress. An early event in this activation is the recruitment and phosphorylation of RPA, a single stranded DNA binding complex composed of three subunits, R...

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Detalles Bibliográficos
Autores principales: Fowler, Sandy, Maguin, Pascal, Kalan, Sampada, Loayza, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015067/
https://www.ncbi.nlm.nih.gov/pubmed/29934626
http://dx.doi.org/10.1038/s41598-018-27919-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015067/
https://www.ncbi.nlm.nih.gov/pubmed/29934626
http://dx.doi.org/10.1038/s41598-018-27919-8

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