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HIF stabilization inhibits renal epithelial cell migration and is associated with cytoskeletal alterations

Acute kidney injury (AKI) is a common and potentially lethal complication in the hospitalized patients, with hypoxic injury being as a major cause. The loss of renal tubular epithelial cells (TEC), one of the AKI hallmarks, is potentially followed by tubular regeneration process orchestrated by the...

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Detalles Bibliográficos
Autores principales: Müller, Simon, Djudjaj, Sonja, Lange, Janina, Iacovescu, Mihail, Goppelt-Struebe, Margarete, Boor, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015081/
https://www.ncbi.nlm.nih.gov/pubmed/29934555
http://dx.doi.org/10.1038/s41598-018-27918-9