Cargando…

Calmodulin shuttling mediates cytonuclear signaling to trigger experience-dependent transcription and memory

Learning and memory depend on neuronal plasticity originating at the synapse and requiring nuclear gene expression to persist. However, how synapse-to-nucleus communication supports long-term plasticity and behavior has remained elusive. Among cytonuclear signaling proteins, γCaMKII stands out in it...

Descripción completa

Detalles Bibliográficos
Autores principales: Cohen, Samuel M., Suutari, Benjamin, He, Xingzhi, Wang, Yang, Sanchez, Sandrine, Tirko, Natasha N., Mandelberg, Nataniel J., Mullins, Caitlin, Zhou, Guangjun, Wang, Shuqi, Kats, Ilona, Salah, Alejandro, Tsien, Richard W., Ma, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015085/
https://www.ncbi.nlm.nih.gov/pubmed/29934532
http://dx.doi.org/10.1038/s41467-018-04705-8