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Calmodulin shuttling mediates cytonuclear signaling to trigger experience-dependent transcription and memory
Learning and memory depend on neuronal plasticity originating at the synapse and requiring nuclear gene expression to persist. However, how synapse-to-nucleus communication supports long-term plasticity and behavior has remained elusive. Among cytonuclear signaling proteins, γCaMKII stands out in it...
Autores principales: | Cohen, Samuel M., Suutari, Benjamin, He, Xingzhi, Wang, Yang, Sanchez, Sandrine, Tirko, Natasha N., Mandelberg, Nataniel J., Mullins, Caitlin, Zhou, Guangjun, Wang, Shuqi, Kats, Ilona, Salah, Alejandro, Tsien, Richard W., Ma, Huan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015085/ https://www.ncbi.nlm.nih.gov/pubmed/29934532 http://dx.doi.org/10.1038/s41467-018-04705-8 |
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