Cargando…

Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

The gradual deterioration of cognitive functions in Alzheimer’s disease is paralleled by a hierarchical progression of amyloid-beta and tau brain pathology. Recent findings indicate that toxic oligomers of amyloid-beta may cause propagation of pathology in a prion-like manner, although the underlyin...

Descripción completa

Detalles Bibliográficos
Autores principales: Sardar Sinha, Maitrayee, Ansell-Schultz, Anna, Civitelli, Livia, Hildesjö, Camilla, Larsson, Max, Lannfelt, Lars, Ingelsson, Martin, Hallbeck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015111/
https://www.ncbi.nlm.nih.gov/pubmed/29934873
http://dx.doi.org/10.1007/s00401-018-1868-1