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Development and first evaluation of a novel multiplex real-time PCR on whole blood samples for rapid pathogen identification in critically ill patients with sepsis

Molecular tests may enable early adjustment of antimicrobial therapy and be complementary to blood culture (BC) which has imperfect sensitivity in critically ill patients. We evaluated a novel multiplex real-time PCR assay to diagnose bloodstream pathogens directly in whole blood samples (BSI-PCR)....

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Detalles Bibliográficos
Autores principales: van de Groep, Kirsten, Bos, Martine P., Savelkoul, Paul H. M., Rubenjan, Anna, Gazenbeek, Christel, Melchers, Willem J. G., van der Poll, Tom, Juffermans, Nicole P., Ong, David S. Y., Bonten, Marc J. M., Cremer, Olaf L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015113/
https://www.ncbi.nlm.nih.gov/pubmed/29700761
http://dx.doi.org/10.1007/s10096-018-3255-1