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Development and first evaluation of a novel multiplex real-time PCR on whole blood samples for rapid pathogen identification in critically ill patients with sepsis
Molecular tests may enable early adjustment of antimicrobial therapy and be complementary to blood culture (BC) which has imperfect sensitivity in critically ill patients. We evaluated a novel multiplex real-time PCR assay to diagnose bloodstream pathogens directly in whole blood samples (BSI-PCR)....
Autores principales: | van de Groep, Kirsten, Bos, Martine P., Savelkoul, Paul H. M., Rubenjan, Anna, Gazenbeek, Christel, Melchers, Willem J. G., van der Poll, Tom, Juffermans, Nicole P., Ong, David S. Y., Bonten, Marc J. M., Cremer, Olaf L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015113/ https://www.ncbi.nlm.nih.gov/pubmed/29700761 http://dx.doi.org/10.1007/s10096-018-3255-1 |
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