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Prodomain of Furin Promotes Phospholipid Transfer Protein Proteasomal Degradation in Hepatocytes

BACKGROUND: Phospholipid transfer protein (PLTP) is one of the major modulators of lipoprotein metabolism and atherosclerosis development; however, little is known about the regulation of PLTP. The effect of hepatic prodomain of furin (profurin) expression on PLTP processing and function is investig...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Lei, Xia, Jiang, Hui, Li, Zhiqiang, Creemers, John W. M., Zhang, Ming, Qin, Shucun, Jin, Weijun, Jiang, Xian‐Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015287/
https://www.ncbi.nlm.nih.gov/pubmed/29680823
http://dx.doi.org/10.1161/JAHA.118.008526