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Epigenetic Regulation of Aldosterone Synthase Gene by Sodium and Angiotensin II

BACKGROUND: DNA methylation is believed to be maintained in adult somatic cells. Recent findings, however, suggest that all methylation patterns are not stable. We demonstrate that stimulatory signals can change the DNA methylation status around transcription factor binding sites and a transcription...

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Detalles Bibliográficos
Autores principales: Takeda, Yoshimichi, Demura, Masashi, Wang, Fen, Karashima, Shigehiro, Yoneda, Takashi, Kometani, Mitsuhiro, Hashimoto, Atsushi, Aono, Daisuke, Horike, Shin‐ichi, Meguro‐Horike, Makiko, Yamagishi, Masakazu, Takeda, Yoshiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015301/
https://www.ncbi.nlm.nih.gov/pubmed/29739797
http://dx.doi.org/10.1161/JAHA.117.008281