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Epigenetic Regulation of Aldosterone Synthase Gene by Sodium and Angiotensin II
BACKGROUND: DNA methylation is believed to be maintained in adult somatic cells. Recent findings, however, suggest that all methylation patterns are not stable. We demonstrate that stimulatory signals can change the DNA methylation status around transcription factor binding sites and a transcription...
Autores principales: | Takeda, Yoshimichi, Demura, Masashi, Wang, Fen, Karashima, Shigehiro, Yoneda, Takashi, Kometani, Mitsuhiro, Hashimoto, Atsushi, Aono, Daisuke, Horike, Shin‐ichi, Meguro‐Horike, Makiko, Yamagishi, Masakazu, Takeda, Yoshiyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015301/ https://www.ncbi.nlm.nih.gov/pubmed/29739797 http://dx.doi.org/10.1161/JAHA.117.008281 |
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