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Rac1 Modulates Endothelial Function and Platelet Aggregation in Diabetes Mellitus

BACKGROUND: Vascular complications and abnormal platelet function contribute to morbidity and mortality in diabetes mellitus. We hypothesized that the Rho‐related GTPase protein, Rac1, can influence both endothelial and platelet function and might represent a potential novel therapeutic target in di...

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Detalles Bibliográficos
Autores principales: Schiattarella, Gabriele Giacomo, Carrizzo, Albino, Ilardi, Federica, Damato, Antonio, Ambrosio, Mariateresa, Madonna, Michele, Trimarco, Valentina, Marino, Marina, De Angelis, Elena, Settembrini, Silvio, Perrino, Cinzia, Trimarco, Bruno, Esposito, Giovanni, Vecchione, Carmine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015399/
https://www.ncbi.nlm.nih.gov/pubmed/29626150
http://dx.doi.org/10.1161/JAHA.117.007322