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Mitochondrial Ca(2+) Influx Contributes to Arrhythmic Risk in Nonischemic Cardiomyopathy
BACKGROUND: Heart failure (HF) is associated with increased arrhythmia risk and triggered activity. Abnormal Ca(2+) handling is thought to underlie triggered activity, and mitochondria participate in Ca(2+) homeostasis. METHODS AND RESULTS: A model of nonischemic HF was induced in C57BL/6 mice by hy...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015427/ https://www.ncbi.nlm.nih.gov/pubmed/29627768 http://dx.doi.org/10.1161/JAHA.117.007805 |