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IL‐23R Deficiency Does Not Impact Atherosclerotic Plaque Development in Mice

BACKGROUND: Interleukin‐23 (IL‐23) has been implicated in inflammatory and autoimmune diseases by skewing CD4(+) T helper cells towards a pathogenic Th17 phenotype. In this study we investigated the presence of IL‐23 receptor (IL‐23R)‐expressing cells in the atherosclerotic aorta and evaluated the e...

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Detalles Bibliográficos
Autores principales: Engelbertsen, Daniel, Depuydt, Marie A. C., Verwilligen, Robin A. F., Rattik, Sara, Levinsohn, Erik, Edsfeldt, Andreas, Kuperwaser, Felicia, Jarolim, Petr, Lichtman, Andrew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015431/
https://www.ncbi.nlm.nih.gov/pubmed/29618473
http://dx.doi.org/10.1161/JAHA.117.008257