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Selective effects of 5-HT2C receptor modulation on performance of a novel valence-probe visual discrimination task and probabilistic reversal learning in mice

RATIONALE: Dysregulation of the serotonin (5-HT) system is a pathophysiological component in major depressive disorder (MDD), a condition closely associated with abnormal emotional responsivity to positive and negative feedback. However, the precise mechanism through which 5-HT tone biases feedback...

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Detalles Bibliográficos
Autores principales: Phillips, Benjamin U., Dewan, Sigma, Nilsson, Simon R. O., Robbins, Trevor W., Heath, Christopher J., Saksida, Lisa M., Bussey, Timothy J., Alsiö, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015605/
https://www.ncbi.nlm.nih.gov/pubmed/29682701
http://dx.doi.org/10.1007/s00213-018-4907-7