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The LRRK2 signalling system

The LRRK2 gene is a major contributor to genetic risk for Parkinson’s disease and understanding the biology of the leucine-rich repeat kinase 2 (LRRK2, the protein product of this gene) is an important goal in Parkinson’s research. LRRK2 is a multi-domain, multi-activity enzyme and has been implicat...

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Detalles Bibliográficos
Autores principales: Price, Alice, Manzoni, Claudia, Cookson, Mark R., Lewis, Patrick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015615/
https://www.ncbi.nlm.nih.gov/pubmed/29308544
http://dx.doi.org/10.1007/s00441-017-2759-9