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Transient Receptor Potential Canonical Channels 4 and 5 Mediate Escherichia coli-Derived Thioredoxin Effects in Lipopolysaccharide-Injected Mice

Thioredoxin plays an essential role in bacterial antioxidant machinery and virulence; however, its regulatory actions in the host are less well understood. Reduced human Trx activates transient receptor potential canonical 5 (TRPC5) in inflammation, but there is no evidence of whether these receptor...

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Detalles Bibliográficos
Autores principales: Pereira, Domingos M. S., Mendes, Saulo J. F., Alawi, Khadija, Thakore, Pratish, Aubdool, Aisah, Sousa, Nágila C. F., da Silva, João F. R., Castro, José A., P. Pereira, Ione C., Silva, Luís C. N., Grisotto, Marcos A. G., Monteiro-Neto, Valério, Costa, Soraia K. P., da Costa, Robson, Calixto, João B., Brain, Susan D., Fernandes, Elizabeth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015690/
https://www.ncbi.nlm.nih.gov/pubmed/29983857
http://dx.doi.org/10.1155/2018/4904696