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Transient Receptor Potential Canonical Channels 4 and 5 Mediate Escherichia coli-Derived Thioredoxin Effects in Lipopolysaccharide-Injected Mice
Thioredoxin plays an essential role in bacterial antioxidant machinery and virulence; however, its regulatory actions in the host are less well understood. Reduced human Trx activates transient receptor potential canonical 5 (TRPC5) in inflammation, but there is no evidence of whether these receptor...
Autores principales: | Pereira, Domingos M. S., Mendes, Saulo J. F., Alawi, Khadija, Thakore, Pratish, Aubdool, Aisah, Sousa, Nágila C. F., da Silva, João F. R., Castro, José A., P. Pereira, Ione C., Silva, Luís C. N., Grisotto, Marcos A. G., Monteiro-Neto, Valério, Costa, Soraia K. P., da Costa, Robson, Calixto, João B., Brain, Susan D., Fernandes, Elizabeth S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015690/ https://www.ncbi.nlm.nih.gov/pubmed/29983857 http://dx.doi.org/10.1155/2018/4904696 |
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