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Inhibitory Effects of Compounds and Extracts from Ampelopsis brevipedunculata on IL-6-Induced STAT3 Activation

Ampelopsis brevipedunculata (Maxim.) Trautv. (AB), a traditional East Asian medicine, exhibits protective effects against several inflammatory diseases. Our search for an inhibitor of IL-6-induced JAK2/STAT3 activation revealed that AB ethanolic extract (ABE) had a significant inhibitory effect on I...

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Detalles Bibliográficos
Autores principales: Jang, Hyun-Jae, Lee, Seung-Jae, Lim, Hyung-Jin, Jung, Kyungsook, Lee, Soyoung, Park, Chan Sun, Lee, Seung Woong, Rho, Mun-Chual
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015723/
https://www.ncbi.nlm.nih.gov/pubmed/29984230
http://dx.doi.org/10.1155/2018/3684845