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Metabolomic Analysis by Nuclear Magnetic Resonance Spectroscopy as a New Approach to Understanding Inflammation and Monitoring of Pharmacological Therapy in Children and Young Adults With Cystic Fibrosis

15-F(2t)-Isoprostane, a reliable biomarker of oxidative stress, has been found elevated in exhaled breath condensate (EBC), a non-invasive technique for sampling of airway secretions, in patients with cystic fibrosis (CF). Azithromycin has antioxidant properties in experimental models of CF, but its...

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Detalles Bibliográficos
Autores principales: Montuschi, Paolo, Lucidi, Vincenzina, Paris, Debora, Montemitro, Enza, Shohreh, Rugia, Mores, Nadia, Melck, Dominique, Santini, Giuseppe, Majo, Fabio, Motta, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015879/
https://www.ncbi.nlm.nih.gov/pubmed/29967580
http://dx.doi.org/10.3389/fphar.2018.00595