Plin4-Dependent Lipid Droplets Hamper Neuronal Mitophagy in the MPTP/p-Induced Mouse Model of Parkinson’s Disease

Epidemiological studies have shown that both lipid metabolism disorder and mitochondrial dysfunction are correlated with the pathogenesis of neurodegenerative diseases (NDDs), including Parkinson’s disease (PD). Emerging evidence suggests that deposition of intracellular lipid droplets (LDs) partici...

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Detalles Bibliográficos
Autores principales: Han, Xiaojuan, Zhu, Jialei, Zhang, Xinlei, Song, Qiqi, Ding, Jianhua, Lu, Ming, Sun, Sifan, Hu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015897/
https://www.ncbi.nlm.nih.gov/pubmed/29967574
http://dx.doi.org/10.3389/fnins.2018.00397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015897/
https://www.ncbi.nlm.nih.gov/pubmed/29967574
http://dx.doi.org/10.3389/fnins.2018.00397

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