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Zinc oxide nanoparticles induce toxicity in CAL 27 oral cancer cell lines by activating PINK1/Parkin-mediated mitophagy

BACKGROUND: Tongue squamous cell carcinoma (tongue cancer) is one of the most common malignancies in the oral maxillofacial region. The tumor easily relapses after surgery, and the prognosis remains poor. Recently, zinc oxide nanoparticles (ZnO NPs) were shown to target multiple cancer cell types. I...

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Detalles Bibliográficos
Autores principales: Wang, Jianfeng, Gao, Shutao, Wang, Shuyu, Xu, Zhaonan, Wei, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016020/
https://www.ncbi.nlm.nih.gov/pubmed/29950828
http://dx.doi.org/10.2147/IJN.S165699