Cargando…

Cwp19 Is a Novel Lytic Transglycosylase Involved in Stationary-Phase Autolysis Resulting in Toxin Release in Clostridium difficile

Clostridium difficile is the major etiologic agent of antibiotic-associated intestinal disease. Pathogenesis of C. difficile is mainly attributed to the production and secretion of toxins A and B. Unlike most clostridial toxins, toxins A and B have no signal peptide, and they are therefore secreted...

Descripción completa

Detalles Bibliográficos
Autores principales: Wydau-Dematteis, Sandra, El Meouche, Imane, Courtin, Pascal, Hamiot, Audrey, Lai-Kuen, René, Saubaméa, Bruno, Fenaille, François, Butel, Marie-José, Pons, Jean-Louis, Dupuy, Bruno, Chapot-Chartier, Marie-Pierre, Peltier, Johann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016235/
https://www.ncbi.nlm.nih.gov/pubmed/29895635
http://dx.doi.org/10.1128/mBio.00648-18